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Porphyrins and Phthalocyanines

Materials Research Group

Cationic (porphyrins and phthalocyanines) Microorganisms PDI

Three new cationic thio-pyridinium phthalocyanines (3a5a) were prepared and their potential as photosensitizers (PSs) was determined against Escherichia coli. Derivative 3a was the most effective PS, causing a 5 logs reduction in bioluminescence under white or red lights.

Photochem. Photobiol., 2012, 88 (3), 537-547.

Comparative PDI studies of first and second generation PSs show that cationic chlorins are more promising PSs than the porphyrin ones to inactivate antibiotic resistant Staphylococcus aureus and Pseudomonas aeruginosa  bacteria.

Under Submission, 2012.